BookBeverly A. Teicher, editor.
Contents:
Perspectives on the history and evolution of tumor models
Murine L1210 and P388 leukemias
Transplantable syngeneic rodent tumors: solid tumors in mice
B16 murine melanoma: historical perspective on the development of a solid tumor model
Human tumor xenograft efficacy models
Imaging the steps of metastasis at the macro and cellular level with fluorescent proteins in real time
Patient-derived tumor models and explants
The pediatric preclinical testing program
Imaging efficacy in tumor models
Mammary cancer in rats
Animal models of melanoma
Experimental animal models for investigating renal cell carcinoma pathogenesis and preclinical therapeutic approaches
Animal models of mesothelioma
The use of mouse models to study leukemia/lymphoma and assess therapeutic approaches
Spontaneous companion animal (pet) cancers
Genetically engineered mouse models of pancreatic ductal adenocarcinoma
Transgenic adenocarcinoma of the mouse prostate: a validated model for the identification and characterization of molecular targets and the evaluation of therapeutic agents
The utility of transgenic mouse models for cancer prevention research
Models for evaluation of targeted therapies of invasive and metastatic disease
Animal models of toxicities caused by anti-neoplastic therapy
Bone marrow as a critical normal tissue that limits drug dose/exposure in preclinical models and the clinic
Anesthetic considerations for the study of murine tumor models
Preclinical tumor response end points
Tumor cell survival
Apoptosis in vivo
Transparent window models and intravital microscopy: imaging gene expression, physiological function and therapeutic effects in tumors.